1  个人基本信息

姓名：肖强

职称：教授

学术兼职：世界中医药学会联合会森林康养研究专业委员会第二届理事会理事，湖北省植物生理与分子生物学学会第十一届理事会理事。

研究领域：特色植物资源及道地中药材开发利用

电子邮件：1992022@hbmzu.edu.cn

通讯地址：bat365在线中国登录入口林学园艺学院

2  学习与工作经历

1987.09-1992.06，同济医科大学，预防医学，学士

1992.07-1997.10，武汉石油化工厂职工医院，从事职业医学健康监护和生产场所环境质量检测评价，医师

1997.11-2002.08，武汉石油化工厂职工医院，从事职业医学健康监护和生产场所环境质量检测评价，主治医师

2002.09-2007.06，厦门大学生命科学学院植物学专业，硕博连读，2007年6月毕业，12月获理学博士学位

2007.07-2009.11，湖北民族学院，生物资源保护与利用湖北省重点实验室，从事植物硒营养生理生化研究，讲师

2009.12-2010.10，湖北民族学院，生物资源保护与利用湖北省重点实验室，从事植物硒营养生理生化研究，副教授

2010.11-2013.07，湖北民族学院，生物科学与技术学院，副教授

2013.08-2015.11，湖北民族学院，林学园艺学院，副教授

2015.12-2018.12，湖北民族学院，林学园艺学院，教授

2019.01-至今，bat365在线中国登录入口，林学园艺学院，教授

3  主持科研项目情况

湖北省教育厅，中青年人才项目，Q20092901，一氧化氮和稀土调控作物生长生理过程关系研究，2010-01至2011-12，1.9万元，结题，主持

教育部，科学研究重点项目，209084，典型树木-红树与胡杨抗盐生理及分子基础比较研究，2010-01至2011-12，10万元，结题，主持

国家自然科学基金，地区基金项目，31260057，一氧化氮调控植物硒代谢机制研究， 2013-01至 2016-12，48万元，结题，主持

湖北省科技厅，技术创新重大专项，2019ACA120，道地中药材恩施黄精品种选育与富硒栽培及产品加工关键技术研发，2019-01至2021-12，200万元，结题，主持

湖北省科技厅，中央引导地方科技发展专项，2024BSB013，黄精新品种“黄恩1号”种苗繁育和林下栽培中试，2025.01-2026.12，50万元，在研，主持。

4  主要学术论文（近五年）

[1]刘保山,梁思琪,肖强*. 刺桐叶多糖的酶解提取工艺及生物活性研究[J].bat365在线中国登录入口学报(自然科学版), 2022, 40(03): 274-281. DOI:10.13501/j.cnki.42-1908/n.2022.09.006.

[2]梁思琪,刘保山,宋歌,郑凯，肖强*. 不同种质黄精红外指纹图谱的分析[J].bat365在线中国登录入口学报(自然科学版), 2022, 40(03):255-259. DOI:10.13501/j.cnki.42-1908/n.2022.09.003.

[3]覃红菊,吴心雨,肖强*. 尖叶四照花叶片多糖含量测定及抗氧化活性分析[J].bat365在线中国登录入口学报(自然科学版),2022,40(04):361-366.DOI:10.13501/j.cnki.42-1908/n.2022.12.001.

[4]宋歌,夏娇,肖强*. 湖北黄精叶片挥发油GC-MS分析及抗氧化活性测定[J].bat365在线中国登录入口学报(自然科学版),2022,40(04):374-379+384.DOI:10.13501/j.cnki.42-1908/n.2022.12.003.

[5]郑凯,刘保山,宋歌,梁思琪，肖强*. 比较荧光分光光度法和紫外-可见分光光度法检测刺葡萄叶片总黄酮含量[J].bat365在线中国登录入口学报(自然科学版),2023,41(01):14-18+32.DOI:10.13501/j.cnki.42-1908/n.2023.03.003.

[6]梁思琪,郑祝,管佩瑶, 肖强*. 尖叶四照花籽油理化性质及抗氧化活性分析[J].粮食与油脂,2023,36(05):94-97.

[7]张佳鑫,梁思琪,肖强*, 崔令军. 黄精总黄酮提取工艺优化及抗氧化活性分析[J].湖北林业科技,2024,53(01):37-44.

[8]崔泓实,梁思琪,石广地,崔令军，肖强*. 转录组和代谢组联合分析揭示大叶黄精皂苷生物合成相关酶基因[J].bat365在线中国登录入口学报(自然科学版),2024,42(01):1-10.DOI:10.13501/j.cnki.42-1908/n.2024.03.001.

[9]万小林,粱思琪,崔令军,肖强*. 大叶黄精转录组中SSR位点信息分析[J].北方园艺,2024,(14):104-109.

[10]李春霖,肖强*,张瑛,万松胜，李双龙. 基于ITS序列对两株野生大型真菌的鉴定及系统发育分析[J].湖北林业科技,2024,53(02):46-50.

[11]兰德淼,姚锦坤,嵇常青,肖强*. 基于网络药理学与分子对接探讨淫羊藿治疗类风湿性关节炎的作用机制[J].bat365在线中国登录入口学报(自然科学版),2024,42(03):330-336.DOI:10.13501/j.cnki.42-1908/n.2024.09.004.

[12]Xiaolin Wan, Jiaqi Wu , Xiuzhi Wang , Lingjun Cui , Qiang Xiao*. Accumulation patterns of flavonoids and phenolic acids in different colored sweet potato flesh revealed based on untargeted metabolomics. Food Chemistry: X, 2024, 23: 101551. https://doi.org/10.1016/j.fochx.2024.101551

[13]Xiuzhi Wang , Xiaolin Wan, Jiaqi Wu , Lingjun Cui *, Qiang Xiao*. Comparative study of polysaccharide metabolites in purple, orange, and white Ipomoea batatas tubers. Food Chemistry: X, 2024, 24: 101855. https://doi.org/10.1016/j.fochx.2024.101855.

[14]Wan, X.;Wang, X.; Xiao, Q*. Comparative Metabolomic Analysis of the Nutrient Composition of Different Varieties of Sweet Potato. Molecules, 2024, 29: 5395. https://doi.org/10.3390/molecules29225395.

[15]Wan X, Cui L, Xiao Q*. Metabolomics and network pharmacology-based identification of phenolic acids in Polygonatum kingianum var. grandifolium rhizomes as anticancer/Tumor active ingredients. PLoS ONE, 2024, 19(12): e0315857. https://doi.org/10.1371/journal.pone.0315857

[16]Wan X, Wang J, Zhang J, Cui H, Cui L* and Xiao Q*. Response mechanism of major secondary metabolites of Polygonatum kingianum to selenium nanoparticles. Front. Plant Sci, 2024, 15:1480079. doi: 10.3389/fpls.2024.1480079.

[17]牟贞才,肖强*. 基于网络药理学与分子对接技术探讨厚朴三物汤治疗腹痛的作用机制[J].bat365在线中国登录入口学报(自然科学版),2024, 42(04): 565-572. DOI:10.13501/j.cnki.42-1908/n.2024.12.014.

[18]Wan X, Xiao Q*. Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of flavonoid biosynthesis in Polygonatum. PLoS ONE, 2025, 20(1): e0318026. https://doi.org/10.1371/journal.pone.0318026.

[19]朱天润,万小林,粱思琪,肖强*. 大叶黄精和黄精中与有机酸代谢相关的bHLH转录因子家族分析[J].湖北农业科学, 2025, 64(02): 202-206. DOI:10.14088/j.cnki.issn0439-8114.2025.02.032.

[20]万小林,粱思琪,肖强*. 黄精中与生物碱代谢相关WRKY转录因子家族分析[J/OL].分子植物育种, 1-9[2025-03-05].  http://kns.cnki.net/kcms/detail/46.1068.S.20240521.1334.007.html.

[21] Wang, XZ (Wang, Xiuzhi) ; Wan, XL (Wan, Xiaolin) ; Zhu, TR (Zhu, Tianrun) ; Cui, LJ (Cui, Lingjun) ; Xiao, Q* (Xiao, Qiang). Metabolomics combined with network pharmacology reveals the anti-hepatoma effects of terpenoids from Polygonatum kingianum var. grandifolium and Polygonatum sibiricum Redouté as well as differences in their terpenoid metabolites. BMC Plant Biology, 2025, 25(1): 769. DOI: 10.1186/s12870-025-06807-0

[22] Wan, XL (Wan, Xiaolin), Wang, XZ (Wang, Xiuzhi) , Zhu, TR (Zhu, Tianrun) , Shi, GD (Shi, Guangdi), Xiao, Q* (Xiao, Qiang). Comparative metabolomics analysis of purple sweet potato flesh across different storage periods. Postharvest Biology and Technology, 2025, 229: 113730. DOI: 10.1016/j.postharvbio.2025.113730

[23] Wang, XZ (Wang, Xiuzhi), Cui, LJ (Cui, Lingjun), Xiao, Q* (Xiao, Qiang). Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of amino acids and their derivatives biosynthesis in Polygonatum. PLOS ONE, 2025, 20(6): e0327145. DOI: 10.1371/journal.pone.0327145

[24] Shi, G (Shi, G.), Lan, D (Lan, D.), Xiao, Q (Xiao, Q.), Huang, C (Huang, C.),  Hong, J* (Hong, J.). Exploring metabolomic and transcriptomic insights into lignan biosynthesis pathways in Polygonatum sibiricum and Polygonatum kingianum var. grandifolium. Applied Ecology and Environmental Research, 23(5): 9413-9424. DOI: 10.15666/aeer/2305_94139424

[25] Wan, XL (Wan, Xiaolin), Wu, JQ (Wu, Jiaqi), Wang, XZ (Wang, Xiuzhi),  Zhou, DZ (Zhou, Dazhai), Xiao, Q* (Xiao, Qiang). Continuous cultivation of Rheum officinale Baill. had a significant effect on physicochemical properties, enzyme activities, microbial communities, and rhizosphere metabolism in soil. Plant and Soil, 2025, 519(1): 257-279. DOI: 10.1007/s11104-025-08128-5

[26] Wang, XZ (Wang, Xiuzhi), Wu, JQ (Wu, Jiaqi), Wan, XL (Wan, Xiaolin), Zhu, TR (Zhu, Tianrun), Xiao, Q* (Xiao, Qiang). Integrated transcriptome and metabolome analyses reveal divergent developmental in primary rhizome axis and branching rhizomes of Rheum officinale Baill. Journal of Applied Research on Medicinal and Aromatic Plants, 2025, 50: 100691. DOI: 10.1016/j.jarmap.2025.100691

[27] Jia, ZX (Jia, Zixuan), Xiao, Q (Xiao, Qiang) *, Shi, GD (Shi, Guangdi), Wang, XZ (Wang, Xiuzhi). Exploring the Mechanism of Selenium-Biofortified Polygonatum Kingianum in Alzheimer's Disease: An Integrated Metabolomics and Network Pharmacology In Silico Study. Combinatorial Chemistry & High Throughput Screening. 2026, DOI: 10.2174/0113862073411991251130085435

[28] Yin, L (Yin, L. H.), Wang, X (Wang, X. Z.), Xiao, Q* (Xiao, Q.), Cui, L (Cui, L. J.). Metabolic strategies in polygonatum: growth-stress trade-off revealed via multi-omics. Applied Ecology and Environmental Research, 2026, 24(2): 1919-1936. DOI: 10.15666/aeer/2402_19191936

[29] Xiuzhi Wang , Tianrun Zhu , Xiaolin Wan , Qiuduo Lai , Wenyu Cao , Qiang Xiao*. Integrated transcriptomic and metabolomic analyses reveal selenium nanoparticle-associated alkaloid accumulation in Stemona tuberosa Lour. Physiologia Plantarum, 2026, e178(4): e71033. DOI：10.1111/ppl.71033

[30] Lianghua Yin, Jiaqi Wu, Xiuzhi Wang, Zhencai Mou, Juntao Gan, Qiang Xiao*. Rhizome differentiation is associated with metabolic specialization and rhizosphere microbial assembly in Rheum officinale Baill. Plant Cell Reports, 2026, 45(8): 219, DOI: 10.1007/s00299-026-03906-6

[31] Wan, XL (Wan, Xiaolin), Wang, XZ (Wang, Xiuzhi), Chen, MX* (Chen, Moxian) , Cui, LJ* (Cui, Lingjun), Xiao, Q* (Xiao, Qiang). Exploring the metabolic characteristics of fresh-cut sweet potatoes at different storage times based on untargeted metabolomics. Food Chemistry: X, 2026, 37: 104066. DOI: 10.1016/j.fochx.2026.104066